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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FIGN All Species: 12.42
Human Site: S396 Identified Species: 18.22
UniProt: Q5HY92 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5HY92 NP_060556.2 759 82146 S396 R K F S S Q S S R A L T P P S
Chimpanzee Pan troglodytes XP_001153855 674 74011 L337 A S R S R G I L G K F V P P I
Rhesus Macaque Macaca mulatta XP_001097992 759 82110 S396 R K F S S Q S S R A L T P P S
Dog Lupus familis XP_545496 695 74019 Y358 G G D S F G K Y P S P G V G E
Cat Felis silvestris
Mouse Mus musculus Q9ERZ6 759 82080 S396 R K F S S Q S S R A L T P P S
Rat Rattus norvegicus Q6GX84 677 74178 G340 G R S R G I F G K F V P P V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506217 731 78137 P393 G A G R S R G P F G K F I P P
Chicken Gallus gallus Q5ZK92 613 66247 R276 I S T A S V S R P A A N P A T
Frog Xenopus laevis Q6DDU8 655 72133 S317 K S L G A A R S R G L H G K F
Zebra Danio Brachydanio rerio Q503S1 736 79183 S392 S Y G S S K G S L G S M R S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQN8 523 58530 M186 D A V P T G M M N F R K K T L
Honey Bee Apis mellifera XP_625184 585 66969 N248 L G G K I S V N S Q F V C P F
Nematode Worm Caenorhab. elegans O16299 594 66169 P257 A R R A P D I P K R C S N P L
Sea Urchin Strong. purpuratus XP_783737 603 65189 E266 P P V L N K E E A D N S M G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEX2 523 57218 G186 G A R S S T A G K K G A A S K
Baker's Yeast Sacchar. cerevisiae P39955 897 100313 K487 K V P N S S S K K T S S H P S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.6 99.4 72.9 N.A. 97.8 35.5 N.A. 31.6 24.8 35.7 71.2 N.A. 25.2 26.6 26.4 30.8
Protein Similarity: 100 54.9 99.4 79.1 N.A. 99.3 54.9 N.A. 47 42.2 53.4 83.7 N.A. 40.8 46.6 43.3 46.9
P-Site Identity: 100 20 100 6.6 N.A. 100 13.3 N.A. 13.3 26.6 20 20 N.A. 0 6.6 6.6 0
P-Site Similarity: 100 20 100 13.3 N.A. 100 33.3 N.A. 20 40 33.3 26.6 N.A. 6.6 13.3 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. 23.9 25 N.A.
Protein Similarity: N.A. N.A. N.A. 39.2 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 19 0 13 7 7 7 0 7 25 7 7 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 7 0 7 0 0 % C
% Asp: 7 0 7 0 0 7 0 0 0 7 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 7 7 0 0 0 0 0 0 7 % E
% Phe: 0 0 19 0 7 0 7 0 7 13 13 7 0 0 13 % F
% Gly: 25 13 19 7 7 19 13 13 7 19 7 7 7 13 13 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % H
% Ile: 7 0 0 0 7 7 13 0 0 0 0 0 7 0 7 % I
% Lys: 13 19 0 7 0 13 7 7 25 13 7 7 7 7 7 % K
% Leu: 7 0 7 7 0 0 0 7 7 0 25 0 0 0 13 % L
% Met: 0 0 0 0 0 0 7 7 0 0 0 7 7 0 0 % M
% Asn: 0 0 0 7 7 0 0 7 7 0 7 7 7 0 0 % N
% Pro: 7 7 7 7 7 0 0 13 13 0 7 7 38 50 7 % P
% Gln: 0 0 0 0 0 19 0 0 0 7 0 0 0 0 0 % Q
% Arg: 19 13 19 13 7 7 7 7 25 7 7 0 7 0 0 % R
% Ser: 7 19 7 44 50 13 32 32 7 7 13 19 0 13 32 % S
% Thr: 0 0 7 0 7 7 0 0 0 7 0 19 0 7 7 % T
% Val: 0 7 13 0 0 7 7 0 0 0 7 13 7 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _